PDB entry 4n12

View 4n12 on RCSB PDB site
Description: Crystal structure of human E18D DJ-1 in complex with Cu
Class: hydrolase
Keywords: Alpha/beta structure, chaperone, oxidative stress protection, cytosol, nucleus, mitochondria, HYDROLASE
Deposited on 2013-10-03, released 2014-03-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: 0.164
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein DJ-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARK7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99497
      • engineered mutation (17)
    Domains in SCOPe 2.08: d4n12a_
  • Heterogens: CU, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4n12A (A:)
maskralvilakgaeemdtvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasled
akkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfg
skvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaq
vkaplvlkd

    Sequence, based on observed residues (ATOM records): (download) 
    >4n12A (A:)
askralvilakgaeemdtvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasleda
kkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfgs
kvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaqv
kaplvlk