PDB entry 4myw

View 4myw on RCSB PDB site
Description: Structure of HSV-2 gD bound to nectin-1
Class: viral protein/cell adhesion
Keywords: IgV-like core, N-/C-terminal extensions, tandem arranged V-C-C Ig-like domains, receptor binding, cell surface attachment, viral, cellular surface, VIRAL PROTEIN-CELL ADHESION complex
Deposited on 2013-09-28, released 2014-10-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-10-01, with a file datestamp of 2014-09-26.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: 0.198
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Envelope glycoprotein D
    Species: Human herpesvirus 2 [TaxId:10313]
    Gene: gD, US6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03172
      • see remark 999 (29)
    Domains in SCOPe 2.07: d4mywa_
  • Chain 'B':
    Compound: Poliovirus receptor-related protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HVEC, nectin-1, PRR1, PVRL1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Envelope glycoprotein D
    Species: Human herpesvirus 2 [TaxId:10313]
    Gene: gD, US6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03172
      • see remark 999 (29)
    Domains in SCOPe 2.07: d4mywc_
  • Chain 'D':
    Compound: Poliovirus receptor-related protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HVEC, nectin-1, PRR1, PVRL1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4mywA (A:)
    adlkyaladpslkmadpnrfrgknlpvldqltdppgvkrvyhiqpsledpfqppsipitv
    yyavleracrsvllhapseapqivrgasdearkhtynltiawyrmgdncaipitvmeyte
    cpynkslgvcpirtqprwsyydsfsavsednlgflmhapafetagtylrlvkindwteit
    qfilehrarasckyalplrippaacltskayqqgvtvdsigmlprfipenqrtvalyslk
    iagwhgpkppytstllppelsdttnatqpelvpedpedsalledpagthhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4mywA (A:)
    pvldqltdppgvkrvyhiqpsledpfqppsipitvyyavleracrsvllhapseapqivr
    gasdearkhtynltiawyrmgdncaipitvmeytecpynkslgvcpirtqprwsyydsfs
    avsednlgflmhapafetagtylrlvkindwteitqfilehrarasckyalplrippaac
    ltskayqqgvtvdsigmlprfipenqrtvalyslkiagwhgpkppytstllp
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4mywC (C:)
    adlkyaladpslkmadpnrfrgknlpvldqltdppgvkrvyhiqpsledpfqppsipitv
    yyavleracrsvllhapseapqivrgasdearkhtynltiawyrmgdncaipitvmeyte
    cpynkslgvcpirtqprwsyydsfsavsednlgflmhapafetagtylrlvkindwteit
    qfilehrarasckyalplrippaacltskayqqgvtvdsigmlprfipenqrtvalyslk
    iagwhgpkppytstllppelsdttnatqpelvpedpedsalledpagthhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4mywC (C:)
    pvldqltdppgvkrvyhiqpsledpfqppsipitvyyavleracrsvllhapseapqivr
    gasdearkhtynltiawyrmgdncaipitvmeytecpynkslgvcpirtqprwsyydsfs
    avsednlgflmhapafetagtylrlvkindwteitqfilehrarasckyalplrippaac
    ltskayqqgvtvdsigmlprfipenqrtvalyslkiagwhgpkppytstllp
    

  • Chain 'D':
    No sequence available.