PDB entry 4mu3
View 4mu3 on RCSB PDB site
Description: The form A structure of an E21Q catalytic mutant of A. thaliana IGPD2 in complex with Mn2+ and a mixture of its substrate, 2R3S-IGP, and an inhibitor, 2S3S-IGP, to 1.12 A resolution
Class: lyase/lyase inhibitor
Keywords: hydro-lyase, histidine biosynthesis, manganese binding, chloroplastic, LYASE-LYASE INHIBITOR complex
Deposited on
2013-09-20, released
2014-09-24
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-09-24, with a file datestamp of
2014-09-19.
Experiment type: XRAY
Resolution: 1.12 Å
R-factor: 0.126
AEROSPACI score: 0.83
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
Species: Arabidopsis thaliana [TaxId:3702]
Gene: At4g14910, dl3495c, HISN5B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4mu3a1, d4mu3a2 - Heterogens: MN, IG2, IYP, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4mu3A (A:)
maspiesarigevkretkqtnvsvkinldghgvsdsstgipfldhmldqlashglfdvhv
ratgdthiddhhtnedvalaigtallkalgerkginrfgdftapldealihvsldlsgrp
ylgynleiptqrvgtydtqlvehffqslvntsgmtlhirqlagknshhiieatfkafara
lrqatesdprrggtipsskgvlsrs
Sequence, based on observed residues (ATOM records): (download)
>4mu3A (A:)
sarigevkretkqtnvsvkinldghgvsdsstgipfldhmldqlashglfdvhvratgdt
hiddhhtnedvalaigtallkalgerkginrfgdftapldealihvsldlsgrpylgynl
eiptqrvgtydtqlvehffqslvntsgmtlhirqlagknshhiieatfkafaralrqate
sdprrg