PDB entry 4mdk

View 4mdk on RCSB PDB site
Description: Cdc34-ubiquitin-CC0651 complex
Class: ligase/ligase inhibitor
Keywords: ubiquitin conjugating enzyme domain, E2 ligase inhibitor, LIGASE-LIGASE INHIBITOR complex
Deposited on 2013-08-22, released 2013-12-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: 0.207
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2 R1
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC34, UBCH3, UBE2R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mdka_
  • Chain 'B':
    Compound: Ubiquitin-conjugating enzyme E2 R1
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC34, UBCH3, UBE2R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mdkb_
  • Chain 'C':
    Compound: Ubiquitin-conjugating enzyme E2 R1
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC34, UBCH3, UBE2R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mdkc_
  • Chain 'D':
    Compound: Ubiquitin-conjugating enzyme E2 R1
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC34, UBCH3, UBE2R1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mdkd_
  • Chain 'E':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG48 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.06: d4mdke1, d4mdke2
  • Chain 'F':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG48 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.06: d4mdkf1, d4mdkf2
  • Chain 'G':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mdkg_
  • Chain 'H':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG48 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.06: d4mdkh1, d4mdkh2
  • Heterogens: U94, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mdkA (A:)
gspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkf
pidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvrtil
lsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkA (A:)
pssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpi
dypysppafrfltkmwhpniyetgdvcisilhppserwnptqnvrtillsvisllnepnt
fspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mdkB (B:)
gspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkf
pidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvrtil
lsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkB (B:)
pssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpi
dypysppafrfltkmwhpniyetgdvcisiwnptqnvrtillsvisllnepntfspanvd
asvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4mdkC (C:)
gspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkf
pidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvrtil
lsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkC (C:)
pssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpi
dypysppafrfltkmwhpniyetgdvcisilhppserwnptqnvrtillsvisllnepnt
fspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4mdkD (D:)
gspssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkf
pidypysppafrfltkmwhpniyetgdvcisilhppvddpqsgelpserwnptqnvrtil
lsvisllnepntfspanvdasvmyrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkD (D:)
pssqkalllelkglqeepvegfrvtlvdegdlynwevaifgppntyyeggyfkarlkfpi
dypysppafrfltkmwhpniyetgdvcnptqnvrtillsvisllnepntfspanvdasvm
yrkwkeskgkdreytdiirkqvlgtkvdaerdgvkvp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4mdkE (E:)
gamgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
sdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkE (E:)
mgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
yniqkestlhlvlrlr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4mdkF (F:)
gamgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
sdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkF (F:)
mgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
yniqkestlhlvlrlr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4mdkG (G:)
gamgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
sdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkG (G:)
qifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyni
qkestlhlvlrlr

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4mdkH (H:)
gamgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtl
sdyniqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mdkH (H:)
mgmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
yniqkestlhlvlr