PDB entry 4m1d
View 4m1d on RCSB PDB site
Description: Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
Class: immune system
Keywords: hiv, v3 loop, antibody-antigen interactions, envelope, immune system
Deposited on
2013-08-02, released
2013-09-04
The last revision prior to the SCOPe 2.04 freeze date was dated
2013-12-25, with a file datestamp of
2013-12-20.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.188
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Fab mAb 447-52D Heavy Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4m1dh1, d4m1dh2 - Chain 'I':
Compound: Fab mAb 447-52D Heavy Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4m1di1, d4m1di2 - Chain 'L':
Compound: Fab mAb 447-52D Light Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4m1dl1, d4m1dl2 - Chain 'M':
Compound: Fab mAb 447-52D Light Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4m1dm1, d4m1dm2 - Chain 'P':
Compound: Cyclic V3 Arch Peptide
Database cross-references and differences (RAF-indexed):
- Chain 'Q':
Compound: Cyclic V3 Arch Peptide
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>4m1dH (H:)
evqlvesggglvkpggslrltcvasgftfsdvwlnwvrqapgkglewvgriksrtdggtt
dyaasvkgrftisrddskntlylqmnslktedtavyscttdgfimirgvsedyyyyymdv
wgkgttvtvssastkgpsvfplapcsrstsggtaalgclvkdyfpepvtvswnsgaltsg
vhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvel
- Chain 'I':
Sequence; same for both SEQRES and ATOM records: (download)
>4m1dI (I:)
evqlvesggglvkpggslrltcvasgftfsdvwlnwvrqapgkglewvgriksrtdggtt
dyaasvkgrftisrddskntlylqmnslktedtavyscttdgfimirgvsedyyyyymdv
wgkgttvtvssastkgpsvfplapcsrstsggtaalgclvkdyfpepvtvswnsgaltsg
vhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvel
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>4m1dL (L:)
qsvltqppsvsaapgqkvtiscsgsssnignnyvlwyqqfpgtapklliygnnkrpsgip
drfsgsksgtsatlgitglqtgdeadyfcatwdsglsadwvfgggtkltvlsqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptec
- Chain 'M':
Sequence, based on SEQRES records: (download)
>4m1dM (M:)
qsvltqppsvsaapgqkvtiscsgsssnignnyvlwyqqfpgtapklliygnnkrpsgip
drfsgsksgtsatlgitglqtgdeadyfcatwdsglsadwvfgggtkltvlsqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptec
Sequence, based on observed residues (ATOM records): (download)
>4m1dM (M:)
svltqppsvsaapgqkvtiscsgsssnignnyvlwyqqfpgtapklliygnnkrpsgipd
rfsgsksgtsatlgitglqtgdeadyfcatwdsglsadwvfgggtkltvlsqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvapt
- Chain 'P':
No sequence available.
- Chain 'Q':
No sequence available.