PDB entry 4m0w

View 4m0w on RCSB PDB site
Description: Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin
Class: hydrolase/protein binding
Keywords: papain-like protease-ubiquitin complex, protein hydrolase and deubiquitination, HYDROLASE-PROTEIN BINDING complex
Deposited on 2013-08-02, released 2014-02-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-30, with a file datestamp of 2014-04-25.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.157
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replicase polyprotein 1a
    Species: SARS coronavirus [TaxId:227859]
    Gene: 1a, NSP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C6U8 (Start-318)
      • engineered mutation (111)
    Domains in SCOPe 2.06: d4m0wa1, d4m0wa2
  • Chain 'B':
    Compound: Ubiquitin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4m0wb_
  • Heterogens: ZN, NA, NHE, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4m0wA (A:)
    mevktikvfttvdntnlhtqlvdmsmtygqqfgptyldgadvtkikphvnhegktffvlp
    sddtlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnnsylssvlla
    lqqlevkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthllqhanle
    sakrvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqylvqqes
    sfvmmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkmseykgp
    vtdvfyketsytttikpvslehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4m0wA (A:)
    vktikvfttvdntnlhtqlvdmsmtygqqfgptyldgadvtkikphvnhegktffvlpsd
    dtlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnnsylssvllalq
    qlevkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthllqhanlesa
    krvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqylvqqessf
    vmmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkmseykgpvt
    dvfyketsytttikpvs
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4m0wB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg