PDB entry 4lr6
View 4lr6 on RCSB PDB site
Description: Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment
Class: transcription regulator/inhibitor
Keywords: BET inhibitor, Brd4 first bromodomain, TRANSCRIPTION REGULATOR-INHIBITOR complex
Deposited on
2013-07-19, released
2013-08-07
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: N/A
AEROSPACI score: 0.6
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, BRD4_HUMAN, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4lr6a_ - Heterogens: FMT, 1XA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4lr6A (A:)
gstnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyyki
iktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqk
inelptee
Sequence, based on observed residues (ATOM records): (download)
>4lr6A (A:)
stnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelpt