PDB entry 4lpb

View 4lpb on RCSB PDB site
Description: Crystal structure of a topoisomerase ATPase inhibitor
Class: isomerase/isomerase inhibitor
Keywords: protein-inhibitor complex, ATP binding, structure-based drug design, antimicrobial, virtual screen, ATP binding domain, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2013-07-15, released 2013-10-30
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.195
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Topoisomerase IV subunit B
    Species: Streptococcus pneumoniae [TaxId:171101]
    Gene: parE, spr0756
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4lpba_
  • Heterogens: 1YP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lpbA (A:)
mskkeininnynddaiqvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgf
gdridvtinkdgsltvqdhgrgmptgmhamgiptveviftilhaggkfgqggyktsgglh
gvgssvvnalsswleveitrdgavykqrfenggkpvttlkkigtalksktgtkvtfmpda
tifsttdfkyntiserlnesafllknvtlsltdkrtdeaiefhyen

    Sequence, based on observed residues (ATOM records): (download) 
    >4lpbA (A:)
qvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgfgdridvtinkdgsltv
qdhgrgmptgmhamgiptveviftilhavgssvvnalsswleveitrdgavykqrfengg
kpvttlkkigtalksktgtkvtfmpdatifsttdfkyntiserlnesafllknvtlsltd
krtdeaiefhyen