PDB entry 4lhu

View 4lhu on RCSB PDB site
Description: Crystal Structure of 9C2 TCR bound to CD1d
Class: immune system
Keywords: NKT cells, GammaDelta TCR, CD1d, lipid recognition, PBS-44, IMMUNE SYSTEM
Deposited on 2013-07-01, released 2013-10-02
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 2.87 Å
R-factor: 0.208
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4lhua1, d4lhua2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.04: d4lhub_
  • Chain 'D':
    Compound: 9C2 TCR delta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LHU
    Domains in SCOPe 2.04: d4lhud1, d4lhud2
  • Chain 'G':
    Compound: 9C2 TCR gamma chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LHU
    Domains in SCOPe 2.04: d4lhug1, d4lhug2
  • Heterogens: NAG, BMA, MG, JLS, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4lhuA (A:)
    rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
    lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
    fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqv
    kpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwyl
    ratldvvageaaglscrvkhsslegqdivlywhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lhuA (A:)
    rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
    lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
    fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqv
    kpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwyl
    ratldvvageaaglscrvkhsslegqdivlyw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4lhuB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4lhuD (D:)
    etgaqkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqn
    aksgrysvnfkkaaksvaltisalqledsakyfcalgdpgglntdklifgkgtrvtvepr
    sqphtkpsvfvmkngtnvaclvkefypkdirinlvsskkitefdpaivispsgkynavkl
    gkyedsnsvtcsvqhdnktvhstdfevktdstdhvkpketentkqpsksasglvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lhuD (D:)
    qkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaksg
    rysvnfkkaaksvaltisalqledsakyfcalgdpgglntdklifgkgtrvtveprsqph
    tkpsvfvmkngtnvaclvkefypkdirinlvsskkitefdpaivispsgkynavklgkye
    dsnsvtcsvqhdnktvhstdfe
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >4lhuG (G:)
    etgssnleggtksvtrptrssaeitcdltvinafyihwylhqegkapqrllyydvsnskd
    vlesglspgkyythtprrwswililrnliendsgvyycatwdrgnpkthyykklfgsgtt
    lvvtdkqldadvspkptiflpsiaetklqkagtylcllekffpdvikihwqekksntilg
    sqegntmktndtymkfswltvpeesldkehrcivrhennkngvdqeiifppiktdvitmd
    pkdnasglvpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lhuG (G:)
    gtksvtrptrssaeitcdltvinafyihwylhqegkapqrllyydvsnskdvlesglspg
    kyythtprrwswililrnliendsgvyycatwdrgnpkthyykklfgsgttlvvtdkqld
    advspkptiflpsiaetklqkagtylcllekffpdvikihwqekksntilgsqegntmkt
    ndtymkfswltvpeesldkehrcivrhennkngvdqeiifppiktdv