PDB entry 4lcu
View 4lcu on RCSB PDB site
Description: Structure of KcsA with E118A mutation
Class: TRANSPORT PROTEIN, membrane protein
Keywords: Voltage Gated Potassium Channel, Potassium Channel, TRANSPORT PROTEIN, membrane protein, pH-gated potassium channel
Deposited on
2013-06-23, released
2013-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Fab light chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4lcua1, d4lcua2, d4lcua3 - Chain 'B':
Compound: Fab heavy chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4lcub1, d4lcub2 - Chain 'C':
Compound: pH-gated potassium channel KcsA
Species: Streptomyces lividans [TaxId:1916]
Gene: kcsA, skc1
Database cross-references and differences (RAF-indexed):
- Uniprot P0A334
- engineered mutation (124)
Domains in SCOPe 2.08: d4lcuc_ - Heterogens: K, DGA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4lcuA (A:)
qvqlqqpgaelvkpgasvklsckasgytftsdwihwvkqrpghglewigeiipsygrany
nekiqkkatltadkssstafmqlssltsedsavyycarergdgyfavwgagttvtvssak
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpssswpsetvtcnvahpasstkvdkkivprd
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4lcuB (B:)
dilltqspailsvspgervsfscrasqsigtdihwyqqrtngsprllikyasesisgips
rfsgsgsgtdftlsinsvesedianyycqqsnrwpftfgsgtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn
- Chain 'C':
Sequence, based on SEQRES records: (download)
>4lcuC (C:)
smhhhhhhppmlsgllarlvklllgrhgsalhwraagaatvllvivllagsylavlaerg
apgaqlitypralwwsvetattvgygdlypvtlwgrlvavvvmvagitsfglvtaalatw
fvgraqerrgh
Sequence, based on observed residues (ATOM records): (download)
>4lcuC (C:)
salhwraagaatvllvivllagsylavlaergapgaqlitypralwwsvetattvgygdl
ypvtlwgrlvavvvmvagitsfglvtaalatwfvgraqerrg