PDB entry 4l9t

View 4l9t on RCSB PDB site
Description: Crystal structure of MepR F27L mutant from multidrug resistant S. aureus clinical isolate
Class: transcription
Keywords: winged helix-turn-helix, wHTH, transcription repressor, TRANSCRIPTION
Deposited on 2013-06-18, released 2013-09-11
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-30, with a file datestamp of 2013-10-25.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: 0.172
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MepR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: mepR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5Y812 (0-138)
      • engineered mutation (26)
      • expression tag (139)
    Domains in SCOPe 2.05: d4l9ta_
  • Chain 'B':
    Compound: MepR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: mepR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5Y812 (Start-138)
      • engineered mutation (26)
    Domains in SCOPe 2.05: d4l9tb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4l9tA (A:)
meftysylfrmishemkqkadqkleqlditneqghtlgylyahqqdgltqndiakalqrt
gptvsnllrnlerkkliyryvdaqdtrrkniglttsgiklveaftsifdemeqtlvsqls
eeeneqmkanltkmlsslqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l9tA (A:)
meftysylfrmishemkqkadqkleqlditneqghtlgylyahqqdgltqndiakalqrt
gptvsnllrnlerkkliyryvdaqdtrrkniglttsgiklveaftsifdemeqtlvsqls
eeeneqmkanltkmlsslqh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4l9tB (B:)
meftysylfrmishemkqkadqkleqlditneqghtlgylyahqqdgltqndiakalqrt
gptvsnllrnlerkkliyryvdaqdtrrkniglttsgiklveaftsifdemeqtlvsqls
eeeneqmkanltkmlsslqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4l9tB (B:)
ftysylfrmishemkqkadqkleqlditneqghtlgylyahqqdgltqndiakalqrtgp
tvsnllrnlerkkliyryvdaqdtrrkniglttsgiklveaftsifdemeqtlvsqlsee
eneqmkanltkmlsslq