PDB entry 4kz8

View 4kz8 on RCSB PDB site
Description: Crystal structure of AmpC beta-lactamase in complex with fragment 20 (1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione)
Class: hydrolase/hydrolase inhibitor
Keywords: AMPC beta-lactamase, class C, hydrolase, cephalosporinase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-05-29, released 2014-05-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-07-30, with a file datestamp of 2014-07-25.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: 0.163
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4kz8a_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:83333]
    Gene: ampA, ampC, b4150, JW4111
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4kz8b_
  • Heterogens: 1U6, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4kz8A (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4kz8B (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

    Sequence, based on observed residues (ATOM records): (download) 
    >4kz8B (B:)
qindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelgsvs
ktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpdevk
sssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplklnh
twinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldinek
tlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitpptp
avraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq