PDB entry 4kug

View 4kug on RCSB PDB site
Description: Crystal structure of 3-hydroxybutylryl-CoA dehydrogenase with NAD from Clostridium butyricum
Class: oxidoreductase
Keywords: HCDH C-domain-like/NAD(P)-binding protein, beta-hydroxyacyl-CoA dehydrogenase activity, Oxidoreductase
Deposited on 2013-05-22, released 2014-05-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-05-28, with a file datestamp of 2014-05-23.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.221
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxybutyryl-CoA dehydrogenase
    Species: Clostridium butyricum [TaxId:632245]
    Gene: hbd, CLP_3850
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4kuga1, d4kuga2
  • Chain 'B':
    Compound: 3-hydroxybutyryl-CoA dehydrogenase
    Species: Clostridium butyricum [TaxId:632245]
    Gene: hbd, CLP_3850
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4kugb1, d4kugb2
  • Chain 'C':
    Compound: 3-hydroxybutyryl-CoA dehydrogenase
    Species: Clostridium butyricum [TaxId:632245]
    Gene: hbd, CLP_3850
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4kugc1, d4kugc2
  • Chain 'D':
    Compound: 3-hydroxybutyryl-CoA dehydrogenase
    Species: Clostridium butyricum [TaxId:632245]
    Gene: hbd, CLP_3850
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4kugd1, d4kugd2
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kugA (A:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydyskskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kugA (A:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydysk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4kugB (B:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydyskskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kugB (B:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydysk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4kugC (C:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydyskskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kugC (C:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydysk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4kugD (D:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydyskskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4kugD (D:)
mkkvfvlgagtmgagivqafaakgcevivrdikeefvdrgiatitkslsklvakekitea
dkeeilsrisgttdmklaadcdlvveaaienmkikkeifaeldgickpetilasntssls
itevasatkradkvigmhffnpapvmklvevirgaatsqetfdavkemsesigktpveva
eapgfvvnrilipmineatfilqegvakeedidaamklganhpmgplalgdligldvcla
imdvlynetgdtkyrassllrkyvragwlgrktgkgfydysk