PDB entry 4kre

View 4kre on RCSB PDB site
Description: Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Class: transcription/RNA
Keywords: eukaryotic Argonaute, GENE REGULATION, RNAi, Slicer, TRANSCRIPTION-RNA complex
Deposited on 2013-05-16, released 2013-06-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-17, with a file datestamp of 2013-07-12.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.172
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein argonaute-1
    Species: Homo sapiens [TaxId:9606]
    Gene: AGO1, EIF2C1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4krea1, d4krea2, d4krea3
  • Chain 'R':
    Compound: RNA (5'-r(p*ap*ap*up*ap*up*up*ap*ap*a*ap*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3')
    Species: Spodoptera frugiperda [TaxId:7108]
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kreA (A:)
ameagpsgaaagaylpplqqvfqaprrpgigtvgkpikllanyfevdipkidvyhyevdi
kpdkcprrvnrevveymvqhfkpqifgdrkpvydgkkniytvtalpignervdfevtipg
egkdrifkvsikwlaivswrmlhealvsgqipvplesvqaldvamrhlasmrytpvgrsf
fsppegyyhplgggrevwfgfhqsvrpamwkmmlnidvsatafykaqpviefmcevldir
nideqpkpltdsqrvrftkeikglkvevthcgqmkrkyrvcnvtrrpashqtfplqlesg
qtvectvaqyfkqkynlqlkyphlpclqvgqeqkhtylplevcnivagqrcikkltdnqt
stmikatarsapdrqeeisrlmknasynldpyiqefgikvkddmtevtgrvlpapilqyg
grnraiatpnqgvwdmrgkqfyngieikvwaiacfapqkqcreevlknftdqlrkiskda
gmpiqgqpcfckyaqgadsvepmfrhlkntysglqliivilpgktpvyaevkrvgdtllg
matqcvqvknvvktspqtlsnlclkinvklgginnilvphqrsavfqqpviflgadvthp
pagdgkkpsitavvgsmdahpsrycatvrvqrprqeiiedlsymvrelliqfykstrfkp
triifyrdgvpegqlpqilhyellairdaciklekdyqpgityivvqkrhhtrlfcadkn
erigksgnipagttvdtnithpfefdfylcshagiqgtsrpshyyvlwddnrftadelqi
ltyqlchtyvrctrsvsipapayyarlvafraryhlvdkehdsgegshisgqsngrdpqa
lakavqvhqdtlrtmyfa

    Sequence, based on observed residues (ATOM records): (download) 
    >4kreA (A:)
qqvfqaprrpgigtvgkpikllanyfevdipkidvyhyevdikpdkcprrvnrevveymv
qhfkifgdrkpvydgkkniytvtalpigervdfevtrifkvsikwlaivswrmlhealvs
gqipvplesvqaldvamrhlasmrytpvgrsffsppegyyhplgggrevwfgfhqsvrpa
mwkmmlnidvsatafykaqpviefmcevldirqpkpltdsqrvrftkeikglkvevthcg
krkyrvcnvtrrpashqtfplqlesgqtvectvaqyfkqkynlqlkyphlpclqvghtyl
plevcnivagqrcikkltdnqtstmikatarsapdrqeeisrlmknasynldpyiqefgi
kvkddmtevtgrvlpapilqyggrnraiatpnqgvwdmrgkqfyngieikvwaiacfapq
kqcreevlknftdqlrkiskdagmpiqgqpcfckyaqgadsvepmfrhlkntysglqlii
vilpgktpvyaevkrvgdtllgmatqcvqvknvvktspqtlsnlclkinvklgginnilv
phqrsavfqqpviflgadvthppkkpsitavvgsmdahpsrycatvrvqrprqeiiedls
ymvrelliqfykstrfkptriifyrdgvpegqlpqilhyellairdaciklekdyqpgit
yivvqkrhhtrlfcadknerigksgnipagttvdtnithpfefdfylcshagiqgtsrps
hyyvlwddnrftadelqiltyqlchtyvrctrsvsipapayyarlvafraryhlvdrdpq
alakavqvhqdtlrtmyfa

  • Chain 'R':
    No sequence available.