PDB entry 4kl9

View 4kl9 on RCSB PDB site
Description: Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in the space group C2
Class: oxidoreductase
Keywords: reductase, OXIDOREDUCTASE
Deposited on 2013-05-07, released 2013-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.39 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: dfrA, folA, MT2833, MTV002.28c, Rv2763c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A546 (20-178)
      • expression tag (19)
    Domains in SCOPe 2.08: d4kl9a1, d4kl9a2
  • Heterogens: NDP, P33, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4kl9A (A:)
mgsshhhhhhssglvprgshmvgliwaqatsgvigrggdipwrlpedqahfreitmghti
vmgrrtwdslpakvrplpgrrnvvlsrqadfmasgaevvgsleealtspetwvigggqvy
alalpyatrcevtevdiglpreagdalapvldetwrgetgewrfsrsglryrlysyhrs

    Sequence, based on observed residues (ATOM records): (download) 
    >4kl9A (A:)
hmvgliwaqatsgvigrggdipwrlpedqahfreitmghtivmgrrtwdslpakvrplpg
rrnvvlsrqadfmasgaevvgsleealtspetwvigggqvyalalpyatrcevtevdigl
preagdalapvldetwrgetgewrfsrsglryrlysyhrs