SCOPe 2.06: Structural Classification of Proteins

PDB entry 4k2s

View 4k2s on RCSB PDB site
Description: Crystal structure of the mutant P317A of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg and d-gluconate
Class: isomerase
Keywords: Enolase fold, D-MANNONATE DEHYDRATASE, D-Gluconate, ISOMERASE
Deposited on 2013-04-09, released 2014-04-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-04-09, with a file datestamp of 2014-04-04.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.17
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (1-2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sa1, d4k2sa2, d4k2sa3
Chain 'B':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sb1, d4k2sb2, d4k2sb3
Chain 'C':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (1-2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sc1, d4k2sc2, d4k2sc3
Chain 'D':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sd1, d4k2sd2, d4k2sd3
Chain 'E':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (1-2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2se1, d4k2se2, d4k2se3
Chain 'F':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sf1, d4k2sf2, d4k2sf3
Chain 'G':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sg1, d4k2sg2, d4k2sg3
Chain 'H':
Compound: D-mannonate dehydratase
Species: Chromohalobacter salexigens [TaxId:290398]
Gene: Csal_2974
Database cross-references and differences (RAF-indexed):
- Uniprot Q1QT89 (3-404)
  - expression tag (1-2)
  - engineered mutation (316)
Domains in SCOPe 2.06: d4k2sh1, d4k2sh2, d4k2sh3
Heterogens: GCO, MG, CL, GOL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4k2sA (A:)
mslkirdaytivtcpgrnfvtlkivtesgthgigdatlngremavaayldehvvpaligr
dagriedtwqylyrgaywrrgpvtmtaiaavdmalwdikakaagmplyqllggksrervm
tyahctgqtiedclgevarhvelgyravrvqsgvpgiettygvaktpgeryepadsslpa
ehvwstekylnhapklfaavrerfgddlhvlhdvhhrltpieaarlgkavepyhlfwled
cvpaenqeslrlirehtttplaigevfnsihdcreliqnqwidyirmplthgggitamrr
vadlaslyhvrtgfhgatdlspvclgaaihfdtwvpnfgiqehmphtdetdavfphdyrf
edghflagespghgvdideelaakypyeraslpvnrledgtlwhw