PDB entry 4jzx
View 4jzx on RCSB PDB site
Description: Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-BUTYL-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, IPP and Ca2+
Class: transferase/transferase inhibitor
Keywords: Geranyl Transferase, FPPS, farnesyl pyrophosphate synthase, farnesyl diphosphate synthase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2013-04-03, released
2014-03-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: farnesyl pyrophosphate synthase
Species: Leishmania major [TaxId:5664]
Gene: FPPS, LMJF_22_1360
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4jzxa1, d4jzxa2 - Chain 'B':
Compound: farnesyl pyrophosphate synthase
Species: Leishmania major [TaxId:5664]
Gene: FPPS, LMJF_22_1360
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4jzxb1, d4jzxb2 - Heterogens: IPE, 476, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzxA (A:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4jzxB (B:)
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
qk