PDB entry 4jzd

View 4jzd on RCSB PDB site
Description: Structure of factor VIIA in complex with the inhibitor 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium binding, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2013-04-02, released 2013-08-21
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.166
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'H':
  Compound: Factor VIIa (Heavy Chain)
  Species: Homo sapiens [TaxId:9606]
  Gene: F7
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-253)
  Domains in SCOPe 2.04: d4jzdh_
• Chain 'L':
  Compound: Factor VIIa (Light Chain)
  Species: Homo sapiens [TaxId:9606]
  Gene: F7
  Database cross-references and differences (RAF-indexed):
  • Uniprot P08709 (0-54)
  Domains in SCOPe 2.04: d4jzdl_
• Heterogens: 1NJ, CA, SO4, GOL, HOH

PDB Chain Sequences:

• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4jzdH (H:)
  ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
  lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
  lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
  sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
  seprpgvllrapfp
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4jzdL (L:)
  icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr