PDB entry 4jy4

View 4jy4 on RCSB PDB site
Description: Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody
Class: immune system
Keywords: Broadly neutralizing antibody against HIV-1, HIV-1 Env gp120 subunit, IMMUNE SYSTEM
Deposited on 2013-03-29, released 2013-05-15
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-05-15, with a file datestamp of 2013-05-10.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.192
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PGT121 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4JY4
    Domains in SCOPe 2.03: d4jy4a1, d4jy4a2
  • Chain 'B':
    Compound: PGT121 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4JY4 (0-End)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4jy4A (A:)
sdisvapgetariscgekslgsravqwyqhragqapsliiynnqdrpsgiperfsgspds
pfgttatltitsveagdeadyychiwdsrvptkwvfgggttltvlgqpkaapsvtlfpps
seelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylslt
peqwkshksyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4jy4A (A:)
disvapgetariscgekslgsravqwyqhragqapsliiynnqdrpsgiperfsgspdsp
fgttatltitsveagdeadyychiwdsrvptkwvfgggttltvlgqpkaapsvtlfppss
eelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsltp
eqwkshksyscqvthegstvektvapte

  • Chain 'B':
    No sequence available.