PDB entry 4jxw
View 4jxw on RCSB PDB site
Description: X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with a non-covalent inhibitor 3-{[3-(4-CARBOXYPHENYL)PROPYL]SULFAMOYL}THIOPHENE-2-CARBOXYLIC ACID (compound 6)
Class: hydrolase/hydrolase inhibitor
Keywords: cephalosporinase, beta-lactamase, serine hydrolase, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2013-03-28, released
2014-05-07
The last revision prior to the SCOPe 2.07 freeze date was dated
2014-07-02, with a file datestamp of
2014-06-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.185
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampC, ampA, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4jxwa_ - Chain 'B':
Compound: Beta-lactamase
Species: Escherichia coli [TaxId:83333]
Gene: ampC, ampA, b4150, JW4111
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4jxwb_ - Heterogens: 1MW, PO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4jxwA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4jxwB (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq