PDB entry 4jdc

View 4jdc on RCSB PDB site
Description: Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Class: oxidoreductase
Keywords: pyrroline-5-carboxylate dehydrogenase, Aldehyde dehydrogenase, oxydoreduction, OXIDOREDUCTASE
Deposited on 2013-02-24, released 2013-12-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.172
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 1-pyrroline-5-carboxylate dehydrogenase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: RVBD_1187
    Database cross-references and differences (RAF-indexed):
    • Uniprot I6X0K4 (20-562)
      • engineered mutation (524)
    Domains in SCOPe 2.05: d4jdca_
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4jdcA (A:)
mgsshhhhhhssglvprgshmdaitqvpvpanepvhdyapkspertrlrtelasladhpi
dlphviggrhrmgdgeridvvqphrhaarlgtltnathadaaaaveaamsaksdwaalpf
deraavflraadllagpwrekiaaatmlgqsksvyqaeidavcelidfwrfnvafarqil
eqqpisgpgewnridyrpldgfvyaitpfnftsiagnlptapalmgntviwkpsitqtla
ayltmqlleaaglppgvinlvtgdgfavsdvaladprlagihftgstatfghlwqwvgtn
igryhsyprlvgetggkdfvvahasarpdvlrtalirgafdyqgqkcsavsrafiahsvw
qrmgdellakaaelrygditdlsnyggalidqrafvknvdaierakgaaavtvavggeyd
dsegyfvrptvllsddptdesfvieyfgpllsvhvypderyeqildvidtgsryaltgav
iaddrqavltaldrlrfaagnfyvndkptgavvgrqpfggargsdtndkagsplnllrwt
sarsiketfvaatdhiyphmavd

    Sequence, based on observed residues (ATOM records): (download) 
    >4jdcA (A:)
mdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgeridv
vqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwre
kiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpld
gfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvinl
vtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdfv
vahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdit
dlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptyf
gpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaagnfyvndk
ptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphmavd