PDB entry 4ixh

View 4ixh on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum
Class: oxidoreductase
Keywords: Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, alpha-beta fold, TIM barrel, OXIDOREDUCTASE
Deposited on 2013-01-25, released 2013-04-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-02, with a file datestamp of 2017-07-28.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Cryptosporidium parvum [TaxId:5807]
    Gene: 56k.02, cgd6_20
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6T2 (3-91)
      • linker (92-94)
    • Uniprot Q8T6T2 (95-End)
    Domains in SCOPe 2.08: d4ixha_
  • Chain 'B':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Cryptosporidium parvum [TaxId:5807]
    Gene: 56k.02, cgd6_20
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6T2 (Start-91)
      • linker (92-94)
    • Uniprot Q8T6T2 (95-End)
    Domains in SCOPe 2.08: d4ixhb_
  • Chain 'C':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Cryptosporidium parvum [TaxId:5807]
    Gene: 56k.02, cgd6_20
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6T2 (3-91)
      • linker (92-94)
    • Uniprot Q8T6T2 (95-End)
    Domains in SCOPe 2.08: d4ixhc_
  • Chain 'D':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Cryptosporidium parvum [TaxId:5807]
    Gene: 56k.02, cgd6_20
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T6T2 (Start-91)
      • linker (92-94)
    • Uniprot Q8T6T2 (95-End)
    Domains in SCOPe 2.08: d4ixhd_
  • Heterogens: IMP, EDO, Q21, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ixhA (A:)
snamgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehl
mavgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdv
ivldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsic
ttrivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsila
gteespgekeligdtvykyyrgmgsvgamksgsgdryfqekrpenkmvpegiegrvkykg
emegvvyqlvgglrscmgylgsasieelwkkssyveittsglreshvhdveivkevmnys
k

    Sequence, based on observed residues (ATOM records): (download) 
    >4ixhA (A:)
mgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlmav
gmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdvivl
dsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsicttr
ivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagte
espgekeligdtvykyyrgmgsvgamksgmvpegiegrvkykgemegvvyqlvgglrscm
gylgsasieelwkkssyveittsglreshvhdveiv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ixhB (B:)
snamgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehl
mavgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdv
ivldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsic
ttrivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsila
gteespgekeligdtvykyyrgmgsvgamksgsgdryfqekrpenkmvpegiegrvkykg
emegvvyqlvgglrscmgylgsasieelwkkssyveittsglreshvhdveivkevmnys
k

    Sequence, based on observed residues (ATOM records): (download) 
    >4ixhB (B:)
gtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlmavg
marlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdvivld
sahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsicttri
vagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagtee
spgekeligdtvykyyrgmgsvgamksmvpegiegrvkykgemegvvyqlvgglrscmgy
lgsasieelwkkssyveittsglreshvhdveiv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ixhC (C:)
snamgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehl
mavgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdv
ivldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsic
ttrivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsila
gteespgekeligdtvykyyrgmgsvgamksgsgdryfqekrpenkmvpegiegrvkykg
emegvvyqlvgglrscmgylgsasieelwkkssyveittsglreshvhdveivkevmnys
k

    Sequence, based on observed residues (ATOM records): (download) 
    >4ixhC (C:)
mgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlmav
gmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdvivl
dsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsicttr
ivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagte
espgekeligdtvykyyrgmgsvgamksgmvpegiegrvkykgemegvvyqlvgglrscm
gylgsasieelwkkssyveittsglreshvhdveiv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ixhD (D:)
snamgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehl
mavgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdv
ivldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsic
ttrivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsila
gteespgekeligdtvykyyrgmgsvgamksgsgdryfqekrpenkmvpegiegrvkykg
emegvvyqlvgglrscmgylgsasieelwkkssyveittsglreshvhdveivkevmnys
k

    Sequence, based on observed residues (ATOM records): (download) 
    >4ixhD (D:)
gtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlmavg
marlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdvivld
sahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsicttri
vagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagtee
spgekeligdtvykyyrgmgsvgamksmvpegiegrvkykgemegvvyqlvgglrscmgy
lgsasieelwkkssyveittsglreshvhdveiv