PDB entry 4iwh

View 4iwh on RCSB PDB site
Description: Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei
Class: oxidoreductase
Keywords: Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, glyceraldehyde-3-phosphate, aconitase, GAPDH, OXIDOREDUCTASE
Deposited on 2013-01-23, released 2013-02-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-02-13, with a file datestamp of 2013-02-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.169
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: BTH_II0674, leuB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2T7H6 (8-362)
      • expression tag (5-7)
    Domains in SCOPe 2.06: d4iwha1, d4iwha2
  • Chain 'B':
    Compound: 3-isopropylmalate dehydrogenase
    Species: Burkholderia thailandensis [TaxId:271848]
    Gene: BTH_II0674, leuB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4iwhb_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iwhA (A:)
mahhhhhhmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpda
tlalakeadailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdas
plkpelvagldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriah
vafqaaqkrakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakap
kqfdvivtgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgian
platilsaamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavv
aal

    Sequence, based on observed residues (ATOM records): (download) 
    >4iwhA (A:)
hhhmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpdatlala
keadailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdasplkpe
lvagldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriahvafqa
aqkrakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakapkqfdv
ivtgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgianplati
lsaamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavvaal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4iwhB (B:)
mahhhhhhmkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpda
tlalakeadailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdas
plkpelvagldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriah
vafqaaqkrakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakap
kqfdvivtgnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgian
platilsaamllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavv
aal

    Sequence, based on observed residues (ATOM records): (download) 
    >4iwhB (B:)
mkiavlpgdgigpeivneavkvlnaldekfelehapvggagyeasghplpdatlalakea
dailfgavgdwkydsleralrpeqailglrkhlelfanfrpaicypqlvdasplkpelva
gldilivrelngdiyfgqprgvraapdgpfageregfdtmrysepevrriahvafqaaqk
rakkllsvdksnvletsqfwrdvmidvskeyadvelshmyvdnaamqlakapkqfdvivt
gnmfgdilsdeasmltgsigmlpsasldknnkglyepshgsapdiagkgianplatilsa
amllryslnraeqadrieravktvleqgyrtgdiatpgcrqvgtaamgdavvaal