PDB entry 4iqt

View 4iqt on RCSB PDB site
Description: Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
Class: transferase/transferase inhibitor
Keywords: terminal transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-01-13, released 2013-09-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2013-10-09, with a file datestamp of 2013-10-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.184
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA nucleotidylexotransferase
    Species: Mus musculus [TaxId:10090]
    Gene: DNTT, TDT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4iqta1, d4iqta2, d4iqta3
  • Heterogens: 1FO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iqtA (A:)
hmspspvpgsqnvpapavkkisqyacqrrttlnnynqlftdaldilaendelrenegscl
afmrassvlkslpfpitsmkdtegipclgdkvksiiegiiedgesseakavlnderyksf
klftsvfgvglktaekwfrmgfrtlskiqsdkslrftqmqkagflyyedlvscvnrpeae
avsmlvkeavvtflpdalvtmtggfrrgkmtghdvdflitspeatedeeqqllhkvtdfw
kqqglllycdilestfekfkqpsrkvdaldhfqkcflilkldhgrvhseksgqqegkgwk
airvdlvmcpydrrafallgwtgsrqferdlrryatherkmmldnhalydrtkrvfleae
seeeifahlgldyiepwernamgsshhhhhhssglvprgs

    Sequence, based on observed residues (ATOM records): (download) 
    >4iqtA (A:)
kisqyacqrrttlnnynqlftdaldilaendelrenegsclafmrassvlkslpfpitsm
kdtegipclgdkvksiiegiiedgesseakavlnderyksfklftsvfgvglktaekwfr
mgfrtlskiqsdkslrftqmqkagflyyedlvscvnrpeaeavsmlvkeavvtflpdalv
tmtggfrrgkmtghdvdflitspeatedeeqqllhkvtdfwkqqglllycdilestfekf
kqpsrdaldhfqkcflilkldhgrvhsekegkgwkairvdlvmcpydrrafallgwtgsr
qferdlrryatherkmmldnhalydrtkrvfleaeseeeifahlgldyiepwerna