PDB entry 4ii5

View 4ii5 on RCSB PDB site
Description: Structure of PCDK2/CYCLINA bound to ADP and 1 MAGNESIUM ION
Class: Transferase/Cell Cycle
Keywords: ADP AND MAGNESIUM BINDING, T160 PHOSPHORYLATION, Transferase-Cell Cycle complex
Deposited on 2012-12-19, released 2013-01-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-23, with a file datestamp of 2013-01-18.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.2
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ii5a_
  • Chain 'B':
    Compound: Cyclin-A2
    Species: Mus musculus [TaxId:10090]
    Gene: Ccna, Ccna2, Cyca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ii5b1, d4ii5b2
  • Chain 'C':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ii5c_
  • Chain 'D':
    Compound: Cyclin-A2
    Species: Mus musculus [TaxId:10090]
    Gene: Ccna, Ccna2, Cyca
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4ii5d1, d4ii5d2
  • Heterogens: ADP, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4ii5A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ii5A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4ii5B (B:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetlsv
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ii5B (B:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetl
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4ii5C (C:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ii5C (C:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4ii5D (D:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetlsv
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ii5D (D:)
    vpdyqedihtylremevkckpkvgymkrqpditnsmrailvdwlvevgeeyklqnetlhl
    avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtyskkqvlrm
    ehlvlkvlafdlaaptvnqfltqyflhlqpanckveslamflgelslidadpylkylpsl
    iagaafhlalytvtgqswpeslaqqtgytleslkpclvdlhqtylkapqhaqqsirekyk
    hskyhsvsllnppetls