PDB entry 4iaa

View 4iaa on RCSB PDB site
Description: Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine
Class: transferase
Keywords: pim1 kinase/oncogene/thioridazine, Ser/Thr kinase, thioridazine, TRANSFERASE
Deposited on 2012-12-06, released 2013-12-18
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-12-18, with a file datestamp of 2013-12-13.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.187
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4iaaa_
  • Heterogens: RTZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4iaaA (A:)
gphmkekeplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngt
rvpmevvllkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeela
rsffwqvleavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgt
rvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecq
hlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >4iaaA (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh