PDB entry 4i8w

View 4i8w on RCSB PDB site
Description: Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL007
Class: hydrolase/hydrolase inhibitor
Keywords: HIV-1 protease, HIV-1 protease-inhibitor complex, Hydrolase, GRL007, protease inhibitor, non-peptidic protease inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-12-04, released 2013-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.195
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: Human immunodeficiency virus type 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0C6F2 (0-98)
  Domains in SCOPe 2.08: d4i8wa_
• Chain 'B':
  Compound: Protease
  Species: Human immunodeficiency virus type 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0C6F2 (0-98)
  Domains in SCOPe 2.08: d4i8wb_
• Heterogens: G07, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4i8wA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4i8wB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf