PDB entry 4i15

View 4i15 on RCSB PDB site
Description: Crystal structure of TbrPDEB1
Class: hydrolase
Keywords: parasite PDE, sleeping sickness, African Trypanosomiasis, HYDROLASE
Deposited on 2012-11-20, released 2013-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-03-27, with a file datestamp of 2013-03-22.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.204
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Class 1 phosphodiesterase PDEB1
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: PDEB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4i15a_
  • Chain 'B':
    Compound: Class 1 phosphodiesterase PDEB1
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: PDEB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4i15b_
  • Heterogens: ZN, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4i15A (A:)
knvpsravkrvtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrl
llgsglpqkfgcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyeklt
elecfvllitalvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsd
pesdvfdglegaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtme
iilkagdisnvtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqi
gfidfvaapffqkivdaclqgmqwtvdriksnraqwervletr

    Sequence, based on observed residues (ATOM records): (download) 
    >4i15A (A:)
vtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrlllgsglpqkf
gcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyekltelecfvllit
alvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsdpesdvfdgle
gaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtmeiilkagdisn
vtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqigfidfvaapf
fqkivdaclqgmqwtvdriksnraqwervletr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4i15B (B:)
knvpsravkrvtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrl
llgsglpqkfgcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyeklt
elecfvllitalvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsd
pesdvfdglegaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtme
iilkagdisnvtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqi
gfidfvaapffqkivdaclqgmqwtvdriksnraqwervletr

    Sequence, based on observed residues (ATOM records): (download) 
    >4i15B (B:)
vtaitkvereavlvcelpsfdvtdvefdlfrarestdkpldvaaaiayrlllgsglpqkf
gcsdevllnfilqcrkkyrnvpyhnfyhvvdvcqtihtflyrgnvyekltelecfvllit
alvhdldhmglnnsfylktesplgilssasgntsvlevhhcnlaveilsdpesdvfdgle
gaertlafrsmidcvlatdmakhgsaleaflasaadqssdeaafhrmtmeiilkagdisn
vtkpfdisrqwamavteefyrqgdmekergvevlpmfdrsknmelakgqigfidfvaapf
fqkivdaclqgmqwtvdriksnraqwervletr