PDB entry 4hjq

View 4hjq on RCSB PDB site
Description: SHP-1 catalytic domain WPD loop closed
Class: hydrolase
Keywords: Phosphatase domain, Hydrolase
Deposited on 2012-10-13, released 2013-04-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 6
    Species: Homo sapiens [TaxId:9606]
    Gene: HCP, PTP1C, PTPN6, SHP-1 (PTPN6)
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29350 (22-End)
      • engineered mutation (232)
    Domains in SCOPe 2.08: d4hjqa_
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 6
    Species: Homo sapiens [TaxId:9606]
    Gene: HCP, PTP1C, PTPN6, SHP-1 (PTPN6)
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29350 (22-End)
      • engineered mutation (232)
    Domains in SCOPe 2.08: d4hjqb_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4hjqA (A:)
mhhhhhhgslvprsenlyfqgsgfweefeslqkqevknlhqrlegqrpenkgknryknil
pfdhsrvilqgrdsnipgsdyinanyiknqllgpdenaktyiasqgcleatvndfwqmaw
qensrvivmttrevekgrnkcvpywpevgmqraygpysvtncgehdtteyklrtlqvspl
dngdlireiwhyqylswpdhgvpsepggvlsfldqinqrqeslphagpiivhssagigrt
gtiividmlmenistkgldcdidiqktiqmvraqrsgmvqteaqykfiyvaiaqfiettk
kklevlqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4hjqA (A:)
gfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgrdsnipgsdyi
nanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttrevekgrnkcv
pywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhyqylswpdhgv
psepggvlsfldqinqrqeslphagpiivhssagigrtgtiividmlmenistkgldcdi
diqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4hjqB (B:)
mhhhhhhgslvprsenlyfqgsgfweefeslqkqevknlhqrlegqrpenkgknryknil
pfdhsrvilqgrdsnipgsdyinanyiknqllgpdenaktyiasqgcleatvndfwqmaw
qensrvivmttrevekgrnkcvpywpevgmqraygpysvtncgehdtteyklrtlqvspl
dngdlireiwhyqylswpdhgvpsepggvlsfldqinqrqeslphagpiivhssagigrt
gtiividmlmenistkgldcdidiqktiqmvraqrsgmvqteaqykfiyvaiaqfiettk
kklevlqs

    Sequence, based on observed residues (ATOM records): (download) 
    >4hjqB (B:)
gfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgrdsnipgsdyi
nanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttrevekgrnkcv
pywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhyqylswpdhgv
psepggvlsfldqinqrqeslphagpiivhssagigrtgtiividmlmenistkgldcdi
diqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkkl