PDB entry 4hef

View 4hef on RCSB PDB site
Description: Structure of avibactam bound to Pseudomonas aeruginosa AmpC
Class: hydrolase/hydrolase inhibitor
Keywords: b-lactamase, hydrolase, periplasmic protein, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2012-10-03, released 2013-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Pseudomonas aeruginosa [TaxId:208964]
    Gene: ampC, PA4110
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24735 (0-359)
      • conflict (204)
    Domains in SCOPe 2.08: d4hefa_
  • Heterogens: GOL, NXL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4hefA (A:)
apadrlkalvdaavqpvmkandipglavaislkgephyfsyglaskedgrrvtpetlfei
gsvsktftatlagyaltqdkmrlddrasqhwpalqgsrfdgislldlatytagglplqfp
dsvqkdqaqirdyyrqwqptyapgsqrlysnpsiglfgylaarslgqpferlmeqqvfpa
lgleqthldvpeaalaqyaqgygkrdrplrvgpgpldaegygvktsaadllrfvdanlhp
erldrpwaqaldathrgyykvgdmtqglgweaydwpislkrlqagnstpmalqphriarl
papqalegqrllnktgstngfgayvafvpgrdlglvilanrnypnaervkiayailsgle