PDB entry 4h0n

View 4h0n on RCSB PDB site
Description: Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant
Class: transferase
Keywords: SAH binding, TRANSFERASE
Deposited on 2012-09-09, released 2012-11-14
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-02-27, with a file datestamp of 2013-02-22.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: 0.204
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dnmt2
    Species: Spodoptera frugiperda [TaxId:7108]
    Gene: DNMT2
    Database cross-references and differences (RAF-indexed):
    • PDB 4H0N (Start-332)
      • engineered mutation (260-261)
      • engineered mutation (263)
    Domains in SCOPe 2.03: d4h0na_
  • Chain 'B':
    Compound: dnmt2
    Species: Spodoptera frugiperda [TaxId:7108]
    Gene: DNMT2
    Database cross-references and differences (RAF-indexed):
    • PDB 4H0N (Start-332)
      • engineered mutation (260-261)
      • engineered mutation (263)
    Domains in SCOPe 2.03: d4h0nb_
  • Chain 'C':
    Compound: dnmt2
    Species: Spodoptera frugiperda [TaxId:7108]
    Gene: DNMT2
    Database cross-references and differences (RAF-indexed):
    • PDB 4H0N (Start-332)
      • engineered mutation (260-261)
      • engineered mutation (263)
    Domains in SCOPe 2.03: d4h0nc_
  • Chain 'D':
    Compound: dnmt2
    Species: Spodoptera frugiperda [TaxId:7108]
    Gene: DNMT2
    Database cross-references and differences (RAF-indexed):
    • PDB 4H0N (Start-332)
      • engineered mutation (260-261)
      • engineered mutation (263)
    Domains in SCOPe 2.03: d4h0nd_
  • Heterogens: SAH, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4h0nA (A:)
gmshkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqql
tpqvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenv
kgfenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrde
iitrlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythy
adgtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksy
nlptnismkqcyrllgnsvnvkvisellkilfe

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0nA (A:)
shkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqqltp
qvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenvkg
fenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrdeii
trlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythyad
gtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksynl
ptnismkqcyrllgnsvnvkvisellkilfe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4h0nB (B:)
gmshkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqql
tpqvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenv
kgfenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrde
iitrlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythy
adgtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksy
nlptnismkqcyrllgnsvnvkvisellkilfe

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0nB (B:)
shkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqqltp
qvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenvkg
fenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrdeii
trlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythyad
gtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksynl
ptnismkqcyrllgnsvnvkvisellkilfe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4h0nC (C:)
gmshkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqql
tpqvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenv
kgfenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrde
iitrlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythy
adgtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksy
nlptnismkqcyrllgnsvnvkvisellkilfe

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0nC (C:)
shkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqqltp
qvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenvkg
fenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrdeii
trlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythyad
gtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksynl
ptnismkqcyrllgnsvnvkvisellkilfe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4h0nD (D:)
gmshkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqql
tpqvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenv
kgfenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrde
iitrlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythy
adgtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksy
nlptnismkqcyrllgnsvnvkvisellkilfe

    Sequence, based on observed residues (ATOM records): (download) 
    >4h0nD (D:)
shkilelysgiggmhcawkesgldgeivaavdintvansvykhnfpetnllnrniqqltp
qvikkwnvdtilmsppcqpftrngkylddndprtnsflyligildqldnvdyilmenvkg
fenstvrnlfidklkecnfiyqefllcpstvgvpnsrlryyctarrnnltwpfkrrdeii
trlpkdfgvphslesiieedvdekflvpekmlrcakvfdicyktskrsccftkaythyad
gtgsiftdkprevvqkcyaaaaqneiggekfvelfkelklryftpkevlmimcfpksynl
ptnismkqcyrllgnsvnvkvisellkilfe