PDB entry 4gzs

View 4gzs on RCSB PDB site
Description: N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes
Class: viral protein
Keywords: beta-propella, influenza virus, neuraminidase, hemagglutinin, hemadsorption, viral infection, viral protein
Deposited on 2012-09-06, released 2012-10-17
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-12-05, with a file datestamp of 2012-11-30.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.228
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZS (Start-392)
    Domains in SCOPe 2.04: d4gzsa_
  • Chain 'B':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZS (Start-392)
    Domains in SCOPe 2.04: d4gzsb_
  • Chain 'C':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZS (Start-392)
    Domains in SCOPe 2.04: d4gzsc_
  • Chain 'D':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:119210]
    Database cross-references and differences (RAF-indexed):
    • PDB 4GZS (Start-392)
    Domains in SCOPe 2.04: d4gzsd_
  • Heterogens: CA, EPE, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4gzsA (A:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gzsA (A:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4gzsB (B:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gzsB (B:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4gzsC (C:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gzsC (C:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4gzsD (D:)
gspsraeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgq
gttlnnvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitg
ddknatasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilf
ieegkivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssy
vcsglvgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyet
fkviegwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetev
lwtsnsivvfcgtsgtygtgswpdgadlnlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >4gzsD (D:)
aeyrnwskpqcditgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nvhsnntvrgrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcitgddkna
tasfiyngrlvdsvvswskeilrtqesecvcingtctvvmtdgsasgkadtkilfieegk
ivhtstlsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinikdhsivssyvcsgl
vgdtprkndssssshcldpnneegghgvkgwafddgndvwmgrtinetsrlgyetfkvie
gwsnpksklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkeetevlwtsn
sivvfcgtsgtygtgswpdgadlnlmpi