PDB entry 4gzl

View 4gzl on RCSB PDB site
Description: Crystal structure of RAC1 Q61L mutant
Class: hydrolase
Keywords: Rossmann fold, GTP binding, membrane, HYDROLASE
Deposited on 2012-09-06, released 2012-12-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.189
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1, TC25, MIG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63000 (Start-203)
      • engineered mutation (87)
    Domains in SCOPe 2.03: d4gzla_
  • Chain 'B':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1, TC25, MIG5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63000 (28-End)
      • engineered mutation (87)
    Domains in SCOPe 2.03: d4gzlb_
  • Heterogens: GNP, MG, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4gzlA (A:)
    mgsshhhhhhssglvprgshmenlyfqgqaikcvvvgdgavgktcllisyttnafpgeyi
    ptvfdnysanvmvdgkpvnlglwdtagledydrlrplsypqtdvflicfslvspasfenv
    rakwypevrhhcpntpiilvgtkldlrddkdtieklkekkltpitypqglamakeigavk
    ylecsaltqrglktvfdeairavl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gzlA (A:)
    aikcvvvgdgavgktcllisyttnafpgyiptvfdnysanvmvdkpvnlglwdtagledy
    drlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrddkd
    tieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4gzlB (B:)
    mgsshhhhhhssglvprgshmenlyfqgqaikcvvvgdgavgktcllisyttnafpgeyi
    ptvfdnysanvmvdgkpvnlglwdtagledydrlrplsypqtdvflicfslvspasfenv
    rakwypevrhhcpntpiilvgtkldlrddkdtieklkekkltpitypqglamakeigavk
    ylecsaltqrglktvfdeairavl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gzlB (B:)
    qaikcvvvgdgavgktcllisyttnafpeyiptvfdnysanvmvdgkpvnlglwdtagle
    dydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrdd
    kdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairav