PDB entry 4gsy

View 4gsy on RCSB PDB site
Description: Crystal structure of thymidylate kinase from Staphylococcus aureus bound to inhibitor.
Class: Transferase/Transferase inhibitor
Keywords: Transferase, nucleotide binding, thymidylate kinase activity, ATP binding, kinase activity, transferase activity, Transferase-Transferase inhibitor complex
Deposited on 2012-08-28, released 2012-10-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-02, with a file datestamp of 2012-12-28.
Experiment type: XRAY
Resolution: 1.71 Å
R-factor: 0.189
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:158879]
    Gene: SA0440, SAR0483, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4gsya_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:158879]
    Gene: SA0440, SAR0483, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4gsyb_
  • Heterogens: 0Y5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4gsyA (A:)
    msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
    teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
    nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
    vnadqplenvvedtyqtiikyleki
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gsyA (A:)
    safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdirt
    eamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefain
    glypdltiylnvsaevgreriidqedlkfhekviegyqeiihqrfksvnadqplenvved
    tyqtiikylek
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4gsyB (B:)
    msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
    teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
    nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
    vnadqplenvvedtyqtiikyleki
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gsyB (B:)
    safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegdmdirte
    amlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefaing
    lypdltiylnvsaevgreridqedlkfhekviegyqeiihnesqrfksvnadqplenvve
    dtyqtiikyleki