PDB entry 4gfd

View 4gfd on RCSB PDB site
Description: Thymidylate kinase (TMK) from S. Aureus in complex with TK-666
Class: transferase/transferase inhibitor
Keywords: kinase, thymidine monphosphate, soluble, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-08-03, released 2012-10-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-02, with a file datestamp of 2012-12-28.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.169
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:158879]
    Gene: SA0440, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4gfda_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Staphylococcus aureus subsp. aureus [TaxId:158879]
    Gene: SA0440, tmk
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4gfdb_
  • Heterogens: 0YB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4gfdA (A:)
    msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
    teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
    nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
    vnadqplenvvedtyqtiikyleki
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gfdA (A:)
    safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegmdirtea
    mlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefaingl
    ypdltiylnvsaevgreriidqedlkfhekviegyqeiihqrfksvnadqplenvvedty
    qtiikylek
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4gfdB (B:)
    msafitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegndmdir
    teamlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefai
    nglypdltiylnvsaevgreriiknsrdqnrldqedlkfhekviegyqeiihnesqrfks
    vnadqplenvvedtyqtiikyleki
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gfdB (B:)
    safitfegpegsgkttvinevyhrlvkdydvimtrepggvptgeeirkivlegdmdirte
    amlfaasrrehlvlkvipalkegkvvlcdryidsslayqgyargigveevralnefaing
    lypdltiylnvsaevgreridqedlkfhekviegyqeiihnesqrfksvnadqplenvve
    dtyqtiikyleki