SCOPe 2.04: Structural Classification of Proteins

PDB entry 4ge9

View 4ge9 on RCSB PDB site
Description: Kynurenine Aminotransferase II Inhibitors
Class: transferase/transferase inhibitor
Keywords: Aminotransferase, irreversible inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-08-01, released 2012-11-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-11-07, with a file datestamp of 2012-11-02.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: 0.178
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: AADAT, KAT2
Database cross-references and differences (RAF-indexed):
- Uniprot Q8N5Z0 (0-424)
  - engineered mutation (239-240)
  - expression tag (425-427)
Domains in SCOPe 2.04: d4ge9a_
Chain 'B':
Compound: kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: AADAT, KAT2
Database cross-references and differences (RAF-indexed):
- Uniprot Q8N5Z0 (0-424)
  - engineered mutation (239-240)
  - expression tag (425-427)
Domains in SCOPe 2.04: d4ge9b_
Chain 'C':
Compound: kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: AADAT, KAT2
Database cross-references and differences (RAF-indexed):
- Uniprot Q8N5Z0 (0-424)
  - engineered mutation (239-240)
  - expression tag (425-427)
Domains in SCOPe 2.04: d4ge9c_
Chain 'D':
Compound: kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Species: Homo sapiens [TaxId:9606]
Gene: AADAT, KAT2
Database cross-references and differences (RAF-indexed):
- Uniprot Q8N5Z0 (0-424)
  - engineered mutation (239-240)
  - expression tag (425-427)
Domains in SCOPe 2.04: d4ge9d_
Heterogens: 0L0, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4ge9A (A:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvprgslehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>4ge9A (A:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvp

Chain 'B':
Sequence, based on SEQRES records: (download)

>4ge9B (B:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvprgslehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>4ge9B (B:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvp

Chain 'C':
Sequence, based on SEQRES records: (download)

>4ge9C (C:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvprgslehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>4ge9C (C:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvp

Chain 'D':
Sequence, based on SEQRES records: (download)

>4ge9D (D:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvprgslehhhhhh

Sequence, based on observed residues (ATOM records): (download)

>4ge9D (D:)
mnyarfitaasaarnpspirtmtdilsrgpksmislagglpnpnmfpfktavitvengkt
iqfgeemmkralqyspsagipellswlkqlqiklhnpptihyppsqgqmdlcvtsgsqqg
lckvfemiinpgdnvlldepaysgtlqslhplgcniinvasdesgivpdslrdilsrwkp
edaknpqkntpkflytvpngnnptgnsltserkkeiyelarkydfliieddpyyflqfns
grvptflsmdvdgrviradsfskiissglrigfltgpkpliervilhiqvstlhpstfnq
lmisqllhewgeegfmahvdrvidfysnqkdailaaadkwltglaewhvpaagmflwikv
kgindvkelieekavkmgvlmlpgnafyvdssapspylrasfssaspeqmdvafqvlaql
ikesllvp