PDB entry 4ge8

View 4ge8 on RCSB PDB site
Description: OYE1-W116I complexed with (s)-Carvone
Class: oxidoreductase
Keywords: CARVONE, ENOATE REDUCTASE, ALKENE REDUCTASE, ENENATIOSELECTIVITY, SUBSTRATE FLIPPING, tim barrel, nad(p)h, oxidoreductase
Deposited on 2012-08-01, released 2012-08-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-10-09, with a file datestamp of 2013-10-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.14
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nadph dehydrogenase 1
    Species: Saccharomyces pastorianus [TaxId:27292]
    Gene: OYE1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02899 (Start-399)
      • engineered mutation (116)
    Domains in SCOPe 2.06: d4ge8a_
  • Heterogens: MG, CL, NA, 1PE, FMN, 0WU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ge8A (A:)
msfvkdfkpqalgdtnlfkpikignnellhravippltrmralhpgnipnrdwaveyytq
raqrpgtmiitegafispqaggydnapgvwseeqmvewtkifnaihekksfvwvqlivlg
waafpdnlardglrydsasdnvfmdaeqeakakkannpqhsltkdeikqyikeyvqaakn
siaagadgveihsangyllnqfldphsntrtdeyggsienrarftlevvdalveaighek
vglrlspygvfnsmsggaetgivaqyayvagelekrakagkrlafvhlveprvtnpflte
gegeyeggsndfvysiwkgpviragnfalhpevvreevkdkrtligygrffisnpdlvdr
lekglplnkydrdtfyqmsahgyidyptyeealklgwdkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ge8A (A:)
sfvkdfkpqalgdtnlfkpikignnellhravippltrmralhpgnipnrdwaveyytqr
aqrpgtmiitegafispqaggydnapgvwseeqmvewtkifnaihekksfvwvqlivlgw
aafpdnlardglrydsasdnvfmdaeqeakakkannpqhsltkdeikqyikeyvqaakns
iaagadgveihsangyllnqfldphsntrtdeyggsienrarftlevvdalveaighekv
glrlspygvfnsmsggaetgivaqyayvagelekrakagkrlafvhlveprvtnpflteg
egeyeggsndfvysiwkgpviragnfalhpevvreevkdkrtligygrffisnpdlvdrl
ekglplnkydrdtfyqmsahgyidyptyeealklgwdkk