PDB entry 4gcj

View 4gcj on RCSB PDB site
Description: CDK2 in complex with inhibitor RC-3-89
Class: transferase/transferase inhibitor
Keywords: protein kinase, inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-07-30, released 2012-10-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-05, with a file datestamp of 2013-05-31.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: 0.192
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (8-305)
      • expression tag (2-7)
    Domains in SCOPe 2.07: d4gcja1, d4gcja2
  • Heterogens: EDO, X64, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4gcjA (A:)
    gplgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstairei
    sllkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqll
    qglafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrape
    illgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvts
    mpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkp
    vphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4gcjA (A:)
    lgspefmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisl
    lkelnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqg
    lafchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeil
    lgckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmp
    dykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvp
    hlrl