PDB entry 4g4s

View 4g4s on RCSB PDB site
Description: Structure of Proteasome-Pba1-Pba2 Complex
Class: hydrolase/chaperone
Keywords: Alpha Beta, Ntn-hydrolase, Peptide binding, HYDROLASE-CHAPERONE complex
Deposited on 2012-07-16, released 2012-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-04-10, with a file datestamp of 2013-04-05.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: 0.184
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proteasome component C7-alpha
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: SCL1, PRC2, PRS2, YGL011C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sa_
  • Chain 'B':
    Compound: Proteasome component Y7
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE8, PRS4, YML092C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sb_
  • Chain 'C':
    Compound: Proteasome component Y13
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE9, PRS5, YGR135W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sc_
  • Chain 'D':
    Compound: Proteasome component PRE6
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE6, YOL038W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sd1, d4g4sd2
  • Chain 'E':
    Compound: Proteasome component PUP2
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PUP2, DOA5, YGR253C, G9155
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4se_
  • Chain 'F':
    Compound: Proteasome component PRE5
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE5, YMR314W, YM9924.06
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sf_
  • Chain 'G':
    Compound: Proteasome component C1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE10, PRC1, PRS1, YOR362C, O6650
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sg_
  • Chain 'H':
    Compound: Proteasome component PRE3
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE3, YJL001W, J1407
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sh_
  • Chain 'I':
    Compound: Proteasome component PUP1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PUP1, YOR157C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4si_
  • Chain 'J':
    Compound: Proteasome component PUP3
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PUP3, YER094C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sj_
  • Chain 'K':
    Compound: Proteasome component C11
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE1, YER012W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sk_
  • Chain 'L':
    Compound: Proteasome component PRE2
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE2, DOA3, PRG1, YPR103W, P8283.10
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sl_
  • Chain 'M':
    Compound: Proteasome component C5
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE7, PRS3, PTS1, YBL041W, YBL0407
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sm_
  • Chain 'N':
    Compound: Proteasome component PRE4
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PRE4, YFR050C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4g4sn_
  • Chain 'O':
    Compound: Proteasome chaperone 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: PBA1, POC1, YLR199C
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Proteasome assembly chaperone 2
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: ADD66, PBA2, POC2, YKL206C
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, LDZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4g4sA (A:)
msgaaaasaagydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvp
dklldpttvsyifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakr
manlsqiytqraymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeitt
nlenhfkkskidhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaen
ieerlvaiaeqd

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sA (A:)
ydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvpdklldpttvsy
ifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakrmanlsqiytqr
aymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeittnlenhfkkski
dhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaenieerlvaiaeq
d

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4g4sB (B:)
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sB (B:)
ysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamsetlskv
slltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqeatqs
ggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwndele
ledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrkltsqein
drleal

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4g4sC (C:)
mgsrrydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqd
tsteklyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikq
gytqhgglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdy
kddmkvddaielalktlskttdssaltydrlefatirkgandgevyqkifkpqeikdilv
ktgitkkdedeeadedmk

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sC (C:)
ydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqdtstek
lyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikqgytqh
gglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdykddmk
vddaielalktlskttdltydrlefatirkgandgevyqkifkpqeikdilvktgit

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4g4sD (D:)
msgydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtrit
pskvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqry
tqsggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknyd
rkeppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqek
qeqqeqdkkkksnh

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sD (D:)
sifspdghifqveyaleavkrgtcavgvkgkncvvlgcerklqdtritpskvskidshvv
lsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytqsggvrpfgvs
tliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrkeppatveecv
kltvrsllevvnieitvvkpdsdivalsseeinqyvtqie

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4g4sE (E:)
mfltrseydrgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratsplle
sdsiekiveidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdla
lrfgegasgeerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaq
aellnewhssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaeli
kelkekeaaespeeadvems

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sE (E:)
mfltrseydrgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratsplle
sdsiekiveidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdla
lrfgegasgeerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaq
aellnewhssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaeli
kelkekeaa

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4g4sF (F:)
mfrnnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyq
kkiikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqknt
qsyggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfi
kidgnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4g4sG (G:)
mtsigtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllv
pqknvkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyv
qahtlynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklv
dhhpeglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeai
dfaqkeingdddededdsdnvmssddenapvatnanattdqegdihle

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sG (G:)
mtsigtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllv
pqknvkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyv
qahtlynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklv
dhhpeglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeai
dfaqke

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4g4sH (H:)
tsimavtfkdgvilgadsrtttgayianrvtdkltrvhdkiwccrsgsaadtqaiadivq
yhlelytsqygtpstetaasvfkelcyenkdnltagiivagyddknkgevytiplggsvh
klpyaiagsgstfiygycdknfrenmskeetvdfikhslsqaikwdgssggvirmvvlta
agverlifypdeyeql

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4g4sI (I:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcagagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicdiqeeqvdita

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sI (I:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcagagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivni

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4g4sJ (J:)
msdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdv
ttlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpf
iagfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdal
sgwgavvyiikkdevvkrylkmrqd

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sJ (J:)
dpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvtt
lnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfia
gfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdalsg
wgavvyiikkdevvkrylkmrqd

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >4g4sK (K:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddfqaq

    Sequence, based on observed residues (ATOM records): (download) 
    >4g4sK (K:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddf

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4g4sL (L:)
tttlafrfqggiivavdsratagnwvasqtvkkvieinpfllgtmaggaadcqfwetwlg
sqcrlhelrekerisvaaaskilsnlvyqykgaglsmgtmicgytrkegptiyyvdsdgt
rlkgdifcvgsgqtfaygvldsnykwdlsvedalylgkrsilaaahrdaysggsvnlyhv
tedgwiyhgnhdvgelfwkvkeeegsfnnvig

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4g4sM (M:)
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4g4sN (N:)
tqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgdntvvgisgdisdm
qhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskmnplwnaiivagvq
sngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipkttvqvaeeaivna
mrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikgygtqki

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.