PDB entry 4fqs
View 4fqs on RCSB PDB site
Description: Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed
Class: transferase/transferase inhibitor
Keywords: Transferase, Folate binding, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2012-06-25, released
2013-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-15, with a file datestamp of
2017-11-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Thymidylate synthase
Species: Mycobacterium tuberculosis [TaxId:83332]
Gene: MT2834, MTV002.29c, Rv2764c, thyA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fqsa_ - Chain 'B':
Compound: Thymidylate synthase
Species: Mycobacterium tuberculosis [TaxId:83332]
Gene: MT2834, MTV002.29c, Rv2764c, thyA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fqsb_ - Heterogens: UMP, LYA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4fqsA (A:)
mtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayell
wflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllr
tdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnias
yallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsife
ytyedivvknydphpaikapvav
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4fqsB (B:)
mtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayell
wflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllr
tdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnias
yallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsife
ytyedivvknydphpaikapvav