PDB entry 4fkw

View 4fkw on RCSB PDB site
Description: Crystal structure of the cdk2 in complex with oxindole inhibitor
Class: transferase/transferase inhibitor
Keywords: alpha and beta protein (a+b), transferase, transferase-transferase inhibitor complex
Deposited on 2012-06-13, released 2013-05-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.179
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4fkwa_
  • Heterogens: 62K, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4fkwA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4fkwA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirlgvpstaireisllkelnhpnivk
    lldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
    rdlkpqnllintegaikladfglavvtlwyrapeillgckyystavdiwslgcifaemvt
    rralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpplded
    grsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl