PDB entry 4fc6

View 4fc6 on RCSB PDB site
Description: Studies on DCR shed new light on peroxisomal beta-oxidation: Crystal structure of the ternary complex of pDCR
Class: oxidoreductase
Keywords: SDR/Rossmann fold, peroxisomal beta-oxidation, OXIDOREDUCTASE
Deposited on 2012-05-24, released 2012-07-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-24, with a file datestamp of 2013-07-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.159
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisomal 2,4-dienoyl-CoA reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: DECR2, PDCR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4fc6a_
  • Chain 'B':
    Compound: Peroxisomal 2,4-dienoyl-CoA reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: DECR2, PDCR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4fc6b_
  • Chain 'C':
    Compound: Peroxisomal 2,4-dienoyl-CoA reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: DECR2, PDCR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4fc6c_
  • Chain 'D':
    Compound: Peroxisomal 2,4-dienoyl-CoA reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: DECR2, PDCR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4fc6d_
  • Heterogens: NAP, HXC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4fc6A (A:)
aqpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrs
lprvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcp
agalsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsa
kaavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgn
kteiahsvlylasplasyvtgavlvadggawltfpng

    Sequence, based on observed residues (ATOM records): (download) 
    >4fc6A (A:)
pppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrslp
rvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcpag
alsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsaka
avdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgnkt
eiahsvlylasplasyvtgavlvadggawltfpn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4fc6B (B:)
aqpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrs
lprvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcp
agalsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsa
kaavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgn
kteiahsvlylasplasyvtgavlvadggawltfpng

    Sequence, based on observed residues (ATOM records): (download) 
    >4fc6B (B:)
qpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrsl
prvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcpa
galsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsak
aavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgnk
teiahsvlylasplasyvtgavlvadggawltfpng

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4fc6C (C:)
aqpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrs
lprvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcp
agalsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsa
kaavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgn
kteiahsvlylasplasyvtgavlvadggawltfpng

    Sequence, based on observed residues (ATOM records): (download) 
    >4fc6C (C:)
aqpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrs
lprvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcp
agalsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsa
kaavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgn
kteiahsvlylasplasyvtgavlvadggawltfpn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4fc6D (D:)
aqpppdvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrs
lprvltaarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcp
agalsfnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsa
kaavdamtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgn
kteiahsvlylasplasyvtgavlvadggawltfpng

    Sequence, based on observed residues (ATOM records): (download) 
    >4fc6D (D:)
dvegddclpayrhlfcpdllrdkvafitgggsgigfriaeifmrhgchtviasrslprvl
taarklagatgrrclplsmdvrappavmaavdqalkefgridilincaagnflcpagals
fnafktvmdidtsgtfnvsrvlyekffrdhggvivnitatlgnrgqalqvhagsakaavd
amtrhlavewgpqnirvnslapgpisgteglrrlggpqaslstkvtasplqrlgnkteia
hsvlylasplasyvtgavlvadggawltfpng