PDB entry 4fa8
View 4fa8 on RCSB PDB site
Description: Multi-pronged modulation of cytokine signaling
Class: Viral Protein/Cytokine
Keywords: immunoglobulin-like domains, 4-helix bundle fold, Viral Protein-Cytokine complex
Deposited on
2012-05-21, released
2012-08-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: secreted protein barf1
Species: Human herpesvirus 4 [TaxId:10376]
Gene: BARF1
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: secreted protein barf1
Species: Human herpesvirus 4 [TaxId:10376]
Gene: BARF1
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: secreted protein barf1
Species: Human herpesvirus 4 [TaxId:10376]
Gene: BARF1
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: macrophage colony-stimulating factor 1
Species: Homo sapiens [TaxId:9606]
Gene: Csf1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fa8e1, d4fa8e2 - Chain 'F':
Compound: macrophage colony-stimulating factor 1
Species: Homo sapiens [TaxId:9606]
Gene: Csf1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fa8f1, d4fa8f2 - Chain 'G':
Compound: macrophage colony-stimulating factor 1
Species: Homo sapiens [TaxId:9606]
Gene: Csf1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4fa8g1, d4fa8g2 - Heterogens: NAG, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>4fa8E (E:)
dpseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaecss
Sequence, based on observed residues (ATOM records): (download)
>4fa8E (E:)
dpseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaec
- Chain 'F':
Sequence, based on SEQRES records: (download)
>4fa8F (F:)
dpseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaecss
Sequence, based on observed residues (ATOM records): (download)
>4fa8F (F:)
dpseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaecs
- Chain 'G':
Sequence; same for both SEQRES and ATOM records: (download)
>4fa8G (G:)
dpseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaecss