PDB entry 4f3j

View 4f3j on RCSB PDB site
Description: Crystal Structure of Trimeric gC1q Domain of Human C1QTNF5 associated with Late-onset Retinal Macular Degeneration
Class: signaling protein
Keywords: Late-onset Retinal Macular Degeneration, L-ORMD, L-ORD, AMD, age-related macular degeneration, C1QTNF5, CTRP5, S163R, Ser163Arg, drusen, retinal deposites, 10-strand jelly-roll fold, MFRP, RPE, ciliary body, SIGNALING PROTEIN
Deposited on 2012-05-09, released 2012-11-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-12-12, with a file datestamp of 2012-12-07.
Experiment type: XRAY
Resolution: 1.34 Å
R-factor: 0.138
AEROSPACI score: 0.74 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Complement C1q tumor necrosis factor-related protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: C1QTNF5, CTRP5, UNQ303/PRO344
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BXJ0 (1-141)
      • expression tag (0)
      • expression tag (142)
    Domains in SCOPe 2.06: d4f3ja1, d4f3ja2, d4f3ja3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4f3jA (A:)
    arsafsakrsesrvpppsdaplpfdrvlvneqghydavtgkftcqvpgvyyfavhatvyr
    aslqfdlvkngesiasffqffggwpkpaslsggamvrlepedqvwvqvgvgdyigiyasi
    ktdstfsgflvysdwhsspvfahhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4f3jA (A:)
    arsafsakrsesrvpppsdaplpfdrvlvneqghydavtgkftcqvpgvyyfavhatvyr
    aslqfdlvkngesiasffqffggwpkpaslsggamvrlepedqvwvqvgvgdyigiyasi
    ktdstfsgflvysdwhsspvfah