PDB entry 4ey4

View 4ey4 on RCSB PDB site
Description: Crystal Structure of Recombinant Human Acetylcholinesterase in the Apo state
Class: hydrolase
Keywords: acetylcholinesterase, hydrolase, apo
Deposited on 2012-05-01, released 2012-10-17
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-12-12, with a file datestamp of 2012-12-07.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: 0.185
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4ey4a_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4ey4b_
  • Heterogens: EDO, NAG, NO3, PE8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ey4A (A:)
gredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvd
attfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygg
gfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalq
wvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgm
gearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvp
vvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraefla
gvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaq
garvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywa
nfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls
at

    Sequence, based on observed residues (ATOM records): (download) 
    >4ey4A (A:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdgdfls
dtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpq
vsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayv
fehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdp
neprdpqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ey4B (B:)
gredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvd
attfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygg
gfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalq
wvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgm
gearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvp
vvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraefla
gvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaq
garvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywa
nfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls
at

    Sequence, based on observed residues (ATOM records): (download) 
    >4ey4B (B:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcpptggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvdg
dflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrv
gvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarv
yayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfar
tgdpneppkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsa