PDB entry 4ew2
View 4ew2 on RCSB PDB site
Description: The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF.
Class: transferase/transferase inhibitor
Keywords: TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2012-04-26, released
2013-07-31
The last revision prior to the SCOPe 2.06 freeze date was dated
2013-08-21, with a file datestamp of
2013-08-16.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.182
AEROSPACI score: 0.59
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Trifunctional purine biosynthetic protein adenosine-3
Species: Homo sapiens [TaxId:9606]
Gene: GART, PGFT, PRGS
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4ew2a1, d4ew2a2 - Heterogens: PO4, SO4, DXY, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4ew2A (A:)
arvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhkl
yknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsna
heqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpaa
lqlvasgtvqlgengkicwvkeehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>4ew2A (A:)
arvavlisgtgsnlqalidstrepnssaqidivisnkaavagldkaeragiptrvinhkl
yknrvefdsaidlvleefsidivclagfmrilsgpfvqkwngkmlnihpsllpsfkgsna
heqaletgvtvtgctvhfvaedvdagqiilqeavpvkrgdtvatlservklaehkifpaa
lqlvasgtvqlgengkicwvkeehh