PDB entry 4ek8

View 4ek8 on RCSB PDB site
Description: Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor
Class: transferase/transferase inhibitor
Keywords: ALPHA AND BETA PROTEIN (A+B), TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2012-04-09, released 2013-05-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-05-29, with a file datestamp of 2013-05-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.184
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4ek8a_
  • Heterogens: 16K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ek8A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ek8A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaemv
trralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpplde
dgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl