PDB entry 4ej7

View 4ej7 on RCSB PDB site
Description: Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, ATP-bound
Class: transferase
Keywords: CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, National Institute of Allergy and Infectious Diseases, EUKARYOTIC PROTEIN KINASE-LIKE FOLD, ALPHA/BETA PROTEIN, TRANSFERASE, PHOSPHOTRANSFERASE, AMINOGLYCOSIDE PHOSPHOTRANSFERASE, ANTIBIOTIC RESISTANCE, AMINOGLYCOSIDES, KANAMYCIN, GTP, INTRACELLULAR
Deposited on 2012-04-06, released 2012-04-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: 0.215
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aminoglycoside 3'-phosphotransferase AphA1-IAB
    Species: ACINETOBACTER BAUMANNII [TaxId:509173]
    Gene: ABAYE3578, AphA1-IAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ej7a_
  • Chain 'B':
    Compound: Aminoglycoside 3'-phosphotransferase AphA1-IAB
    Species: ACINETOBACTER BAUMANNII [TaxId:509173]
    Gene: ABAYE3578, AphA1-IAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ej7b_
  • Chain 'C':
    Compound: Aminoglycoside 3'-phosphotransferase AphA1-IAB
    Species: ACINETOBACTER BAUMANNII [TaxId:509173]
    Gene: ABAYE3578, AphA1-IAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ej7c_
  • Heterogens: ATP, CA, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ej7A (A:)
mgsshhhhhhssgrenlyfqgmshiqretscsrprlnsnldadlygyrwardnvgqsgat
iyrlygkpnapelflkhgkgsvandvtdemvrlnwltafmplptikhfirtpddawlltt
aipgktafqvleeypdsgenivdalavflrrlhsipvcncpfnsdrvfrlaqaqsrmnng
lvdasdfdderngwpveqvwkemhkllpfspdsvvthgdfsldnlifdegkligcidvgr
vgiadryqdlailwnclgefspslqkrlfqkygidnpdmnklqfhlmldeff

    Sequence, based on observed residues (ATOM records): (download) 
    >4ej7A (A:)
shiqretscsrprlnsnldadlygyrwardnvgqsgatiyrlygkpnapelflkhgkgsv
andvtdemvrlnwltafmplptikhfirtpddawllttaipgktafqvleeypdsgeniv
dalavflrrlhsipvcncpfnsdrvfrlaqaqsrmnnglvdasdfdderngwpveqvwke
mhkllpfspdsvvthgdfsldnlifdegkligcidvgrvgiadryqdlailwnclgefsp
slqkrlfqkygidnpdmnklqfhlmldeff

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ej7B (B:)
mgsshhhhhhssgrenlyfqgmshiqretscsrprlnsnldadlygyrwardnvgqsgat
iyrlygkpnapelflkhgkgsvandvtdemvrlnwltafmplptikhfirtpddawlltt
aipgktafqvleeypdsgenivdalavflrrlhsipvcncpfnsdrvfrlaqaqsrmnng
lvdasdfdderngwpveqvwkemhkllpfspdsvvthgdfsldnlifdegkligcidvgr
vgiadryqdlailwnclgefspslqkrlfqkygidnpdmnklqfhlmldeff

    Sequence, based on observed residues (ATOM records): (download) 
    >4ej7B (B:)
qretscsrprlnldadlygyrwardnvgqsgatiyrlygkpnapelflkhgkgsvandvt
demvrlnwltafmplptikhfirtpddawllttaipgktafqvleeypdsgenivdalav
flrrlhsipvcncpfnsdrvfrlaqaqsrmnnglvdasdfdderngwpveqvwkemhkll
pfspdsvvthgdfsldnlifdegkligcidvgrvgiadryqdlailwnclgefspslqkr
lfqkygidnpdmnklqfhlmldeff

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ej7C (C:)
mgsshhhhhhssgrenlyfqgmshiqretscsrprlnsnldadlygyrwardnvgqsgat
iyrlygkpnapelflkhgkgsvandvtdemvrlnwltafmplptikhfirtpddawlltt
aipgktafqvleeypdsgenivdalavflrrlhsipvcncpfnsdrvfrlaqaqsrmnng
lvdasdfdderngwpveqvwkemhkllpfspdsvvthgdfsldnlifdegkligcidvgr
vgiadryqdlailwnclgefspslqkrlfqkygidnpdmnklqfhlmldeff

    Sequence, based on observed residues (ATOM records): (download) 
    >4ej7C (C:)
hiqretscsrprlnsnldadlygyrwardnvgqsgatiyrlygkpnapelflkhgkgsva
ndvtdemvrlnwltafmplptikhfirtpddawllttaipgktafqvleeypdsgenivd
alavflrrlhsipvcncpfnsdrvfrlaqaqsrmnnglvdasdfdderngwpveqvwkem
hkllpfspdsvvthgdfsldnlifdegkligcidvgrvgiadryqdlailwnclgefsps
lqkrlfqkygidnpdmnklqfhlmldeff