PDB entry 4e6a

View 4e6a on RCSB PDB site
Description: p38a-PIA23 complex
Class: transferase
Keywords: MAP kinase, p38, signal transduction, alternative activation modes, lipid binding site, PIA, perifosine, Kinase fold, kinase, substrates, phosphorylation, TRANSFERASE
Deposited on 2012-03-15, released 2012-10-31
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-06-19, with a file datestamp of 2013-06-14.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: 0.224
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4e6aa_
  • Heterogens: 0O9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4e6aA (A:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >4e6aA (A:)
erptfyrqelktiwevperyqnlspvgsvcaafdtktglrvavkklsrpfqsiihakrty
relrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivqkltddhvqfli
yqilrglkyihsadiihrdlkpsnlavnedcelkildfrwyrapeimlnwmhynqtvdiw
svgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpk
mnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsf
esrdllidewksltydevisfvpp