PDB entry 4dxa

View 4dxa on RCSB PDB site
Description: Co-crystal structure of Rap1 in complex with KRIT1
Class: protein binding
Keywords: GTPase, FERM, Protein-protein interaction, GTP binding, Cytoplasmic, PROTEIN BINDING
Deposited on 2012-02-27, released 2012-05-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.198
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Ras-related protein Rap-1b
  Species: Homo sapiens [TaxId:9606]
  Gene: OK/SW-cl.11, RAP1B, Ras-related protein Rap-1b (RAP1B)
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61224 (2-168)
    • expression tag (1)
    • engineered mutation (13)
  Domains in SCOPe 2.06: d4dxaa1, d4dxaa2
• Chain 'B':
  Compound: Krev interaction trapped protein 1
  Species: Homo sapiens [TaxId:9606]
  Gene: CCM1, Krev interaction trapped protein 1 (KRIT1), KRIT1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O00522 (5-End)
    • expression tag (4)
• Heterogens: GSP, MG, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >4dxaA (A:)
  gsmreyklvvlgsvgvgksaltvqfvqgifvekydptiedsyrkqvevdaqqcmleildt
  agteqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkc
  dledervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4dxaA (A:)
  smreyklvvlgsvgvgksaltvqfvqgifvekydptiedsyrkqvevdaqqcmleildta
  gteqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtddvpmilvgnkcd
  ledervvgkeqgqnlarqwnncaflessakskinvneifydlvrqinr
  

  
  
• Chain 'B':
  No sequence available.